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Microbiology — 2025, Undergraduate
This study assessed the presence of antibiotic resistance genes in bacterial isolates recovered from clinical samples. Isolates were tested phenotypically for resistance and screened by molecular methods for selected resistance determinants. The findings revealed that resistance genes were detected in a substantial proportion of resistant isolates, with correlations observed between gene carriage and resistance phenotypes, while some phenotypically resistant isolates lacked the tested genes. The study observed co-occurrence of multiple determinants in several isolates. It recommends combined phenotypic and genotypic surveillance to guide therapy and stewardship.
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